绝对抗体/抗Ara h 2/Ara h 3[PA12P3F10]/200μg/Ab01494-1.1-免疫在线蚂蚁淘旗下平台

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商品详细绝对抗体/抗Ara h 2/Ara h 3[PA12P3F10]/200μg/Ab01494-1.1

绝对抗体/抗Ara h 2/Ara h 3[PA12P3F10]/200μg/Ab01494-1.1

商品编号： Ab01494-1.1

品牌： absoluteantibody

市场价： ¥5400.00

美元价： 3240.00

产地：美国(厂家直采)

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产品分类：功能性抗体

公司分类： Functional_antibody

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商品介绍

UniProtAccessionNumberofTargetProtein:Q6PSU2;O82580

AlternativeName(s)ofTarget:Arah2;Arachishypogaea;peanut;Arah3;Conglutin;2Salbumin;Conglutin-7;2Sprotein1;SeedstorageproteinSSP1;SeedstorageproteinSSP2;Glycinin;Arah3Immunogen:ThisantibodywasacquiredbyisolatingIgEBcellsfromperipheralbloodofhumanindividualsallergictopeanutsandsubsequentcloningandexpressingtheantibody(crooteetal.,2018).

Specificity:ThisantibodyrecognisespredominantlyArah2,butitalsocross-reactswithArah3andweaklywithArah1.Arah2isoneofthemajorpeanutallergens.

ApplicationNotes:ELISAtestsconfirmedthatthisantibodystronglybindsArah2andtoalesserdegreeArah3(Crooteetal.,2018).BiolayerinterferometryexperimentsrevealedthatPA12P3F10antibodyexhibitsveryhighaffinitytoArah2andArah3peanutallergens(Crooteetal.,2018).Consequently,thisantibodyanditsengineeredversions(suchasanIgGversionwiththesamevariabledomainsastheoriginalIgE)mightbeusedinthedevelopmentofthetherapeuticagentsforallergies,assuchIgGscouldcompetewithallergenicIgEsfortheallergen(Crooteetal.,2018).

Antibodyfirstpublishedin:Crooteetal.High-affinityallergen-specifichumanantibodiesclonedfromsingleIgEBcelltranscriptomes.Science.2018Dec14;362(6420):1306-1309.doi:10.1126/science.aau2599.PMID:30545888Noteonpublication:ThisarticledescribesthegenerationandcharacterisationofthePA12P3F10antibody.

品牌介绍

Absolute antibody本公司服务于抗体测序、制造和工程服务提供给所有抗体使用者和不断增长的抗体。Absolute Antibody Ltd was founded in Oxford, UK, in August 2012, with the vision that all antibody users should be able to use recombinant antibodies, which are absolutely defined by their amino acid sequence. This view gained support in 2015 with a Comment in Nature magazine by Bradbury and Pluckthun (+110 co-signatories) – “Reproducibility: Standardize antibodies used in research“. Rather than creating entirely new antibodies (or antibody-like molecules), we are building a catalog by taking existing antibodies (often from hybridomas) then manufacturing them in a superior way and improving their usefulness by engineering.品牌货号名称规格absoluteantibody21 E11Anti-Api m 21 kitabsoluteantibodyBAB2Anti-Bet v 1 1 kitabsoluteantibodyBAB3Anti-Bet v 11 kitabsoluteantibodyBAB4Anti-Bet v 11 kitabsoluteantibodyBAB5Anti-Bet v 1 1 kitabsoluteantibodyBV16Anti-Bet v 1 1 kitabsoluteantibodyM0418Anti-Bet v 11 kitabsoluteantibody4C3Anti-Bla g 2 1 kitabsoluteantibody7C11Anti-Bla g 21 kitabsoluteantibodyD1Anti-Bos d 5 1 kitabsoluteantibody6A8Anti-Der f 11 kitabsoluteantibody10B9Anti-Der p 11 kitabsoluteantibody5H8Anti-Der p 11 kitabsoluteantibody4C1Anti-Neurotoxin AahII1 kitabsoluteantibodyH10Anti-Der p 21 kit

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关注表位标记 Primary Antibodies Recombinant Antibodies from Human Patients Anti-Allergen Antibodies 多标签控制蛋白 Recombinant Isotype Controls 抗过敏原抗体重组F4/80克隆CI:A3-1 体内研究用重组抗体

Recombinant F4/80 Clone CI:A3-1 Research-Grade Biosimilars 关注来自人类患者的重组抗体同型对照重组免疫球蛋白Fc结构域（Ig-Fc结构域）人源性重组抗体研究级生物仿制药其他产品抗病毒抗体重组自由轻链 Antibodies to Epitope Tags Anti-Virus Antibodies Fc融合蛋白其他产品表位标记抗体重组同型对照

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