![绝对抗体/抗-4-1BBL[TKS-1]/200μg/Ab00881-7.1](https://www.ebiomall.cn/images/no_picture.gif)
UniProt Accession Number of Target Protein: P41274
Alternative Name(s) of Target: CD137L; TNFRSF9L; CD134 ligand; 4-1BB Ligand; TNFRSF9; TNFR superfamily 9; tumor necrosis factor receptor superfamily member 9Immunogen: Murine B-cell lymphoma 2PK-3 cells injected into SD rats.
Specificity: This antibody binds to murine 4-1BBL and competes with binding of 4-1BB.
Application Notes: This antibody has been used to detect 4-1BBL by flow cytometry. It is able to block 4-1BBL interacting with 4-1BB and prevent signalling.
Antibody first published in:Futagawa et al.Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells.Int Immunol. 2002 Mar;14(3):275-86PMID:11867564Note on publication:Describes the generation and initialcharacterisation of this antibody.
ELISA of anti-4-1BBL antibody on 4-1BBL-Fc fusion protein. Binding curves of the rabbit IgG chimeric version of the anti-4-1BBL antibody TKS-1 (Ab00881-23.0; red line) and isotype control (Ab00102-23.0, anti-Fluorescein; blue line) to an ELISA plate coated with mouse 4-1BBL Fc-fusion protein (Pr00129-1.28) at a concentration of 5 µg/ml. A 3-fold serial dilution from 10,000 to 0.17 ng/ml was performed using Ab00881-23.0. For signal detection, a 1:4000 dilution of HRP-fused anti-rabit IgG antibody was used.
