UniProt Accession Number of Target Protein: Q05A52
Alternative Name(s) of Target: Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD70; Ki-24 Antigen; CD70 Antigen; TNLG8A; TAN1-7; TAN17Immunogen: Recombinant mouse CD70 (extracellular domain, aa residues 41-195).
Specificity: This antibody binds to mouse CD70.
Application Notes: This antibody can be used to detect mouse CD70, the ligand for CD27. The original rat IgG1 format has been used in vivo to inhibit CD70-CD27mediated induction of interferon gamma following injection of glycolipid activators .
Antibody first published in:Arora et al.A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens.Immunity. 2014 Jan 16;40(1):105-16PMID:24412610Note on publication:Describes the generation and initial characterisation of this antibody and its use in vivo.