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当前位置: 首页 > 产品中心 > Recombinant_antibodies > 绝对抗体/抗PD-L2[TY25]/200μg/Ab00883-2.3
商品详细绝对抗体/抗PD-L2[TY25]/200μg/Ab00883-2.3
绝对抗体/抗PD-L2[TY25]/200μg/Ab00883-2.3
绝对抗体/抗PD-L2[TY25]/200μg/Ab00883-2.3
商品编号: Ab00883-2.3
品牌: absoluteantibody
市场价: ¥5400.00
美元价: 3240.00
产地: 美国(厂家直采)
公司:
产品分类: 重组抗体
公司分类: Recombinant_antibodies
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

UniProt Accession Number of Target Protein: Q9WUL5

Alternative Name(s) of Target: B7-DC; PDL2; B7DC; CD273; programmed death ligand 2; CD273; Pdcd1lg2Immunogen: This antibody was raised by immunising SD rats with B7-DC-transfected RAW264.7 cells and selected on B7-DC-transfected NRK.

Specificity: This antibody binds to mouse PD-L2 and competes with PD-1 binding. It does not cross-react with PD-L1.

Application Notes: This antibody has been used to detect murine PD-L2by flow cytometry on stimulated dendritic cells as well as various mouse tumour cells. It also detects immunoprecipitates mouse PD-L2 and can be used to detect it by non-reducing Western Blot. TY25 inhibits PD-L2 binding to PD-1 transfected cells (Ansari et al. 2003, PMID: 12847137) and thereby blocks PD-L2 : PD-1 signalling.

Antibody first published in:Yamazaki et al.Expression of programmed death 1 ligands by murine T cells and APC.J Immunol. 2002 Nov 15;169(10):5538-45PMID:12421930Note on publication:Describes the generation and initial characterisation of this antibody.

Binding Curve
ELISA using Ab00883-23.0.
Binding Curve

Binding curve of anti-PDL2 antibody TY25 (Ab00883-23.0) to mouse PDL2-Fc fusion protein ELISA Plate coated with mouse PDL2-Fc fusion protein (Pr00156-1.9) at a concentration of 5 µg/ml. A 3-fold serial dilution from 10,000 to 0.1 ng/ml was performed using Ab00883-23.0. For detection, a 1:4000 dilution of HRP-labelled goat anti-rabbit antibody (Bio-Rad) was used.

品牌介绍
Absolute antibody本公司服务于抗体测序、制造和工程服务提供给所有抗体使用者和不断增长的抗体。Absolute Antibody Ltd was founded in Oxford, UK, in August 2012, with the vision that all antibody users should be able to use recombinant antibodies, which are absolutely defined by their amino acid sequence. This view gained support in 2015 with a Comment in Nature magazine by Bradbury and Pluckthun (+110 co-signatories) – “Reproducibility: Standardize antibodies used in research“. Rather than creating entirely new antibodies (or antibody-like molecules), we are building a catalog by taking existing antibodies (often from hybridomas) then manufacturing them in a superior way and improving their usefulness by engineering.品牌货号名称规格absoluteantibody21 E11Anti-Api m 21 kitabsoluteantibodyBAB2Anti-Bet v 1 1 kitabsoluteantibodyBAB3Anti-Bet v 11 kitabsoluteantibodyBAB4Anti-Bet v 11 kitabsoluteantibodyBAB5Anti-Bet v 1 1 kitabsoluteantibodyBV16Anti-Bet v 1 1 kitabsoluteantibodyM0418Anti-Bet v 11 kitabsoluteantibody4C3Anti-Bla g 2 1 kitabsoluteantibody7C11Anti-Bla g 21 kitabsoluteantibodyD1Anti-Bos d 5 1 kitabsoluteantibody6A8Anti-Der f 11 kitabsoluteantibody10B9Anti-Der p 11 kitabsoluteantibody5H8Anti-Der p 11 kitabsoluteantibody4C1Anti-Neurotoxin AahII1 kitabsoluteantibodyH10Anti-Der p 21 kit