UniProt Accession Number of Target Protein: P08514
Alternative Name(s) of Target: Integrin alpha-IIb, Integrin alpha-2b, ITGA2B, platelet glycoprotein IIb of IIb/IIIa complexImmunogen: CD41 is the integrin alpha chain 2b forming a fibrinogen receptor in heterodimeric complex with beta 3.
Specificity: Recognises human CD41.
Antibody first published in:No Authors Listed .Use of a monoclonal antibody directed against the platelet glycoprotein IIb/IIIa receptor in high-risk coronary angioplasty. The EPIC Investigation.N Engl J Med.PMID:8121459
Flow-cytometry using the anti-CD41 research biosimilar antibody Abciximab (7E3, Ab00282) Human lymphocytes were stained with an isotype control (Ab00102-23.0, panel A) or the rabbit-chimeric version of Abciximab (Ab00282-23.0, panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody (ab150073) and cells analysed on a FACSCanto flow-cytometer.