![绝对抗体/抗EGFR[C225（西妥昔单抗）]/50μg/bAb0163](https://www.ebiomall.cn/images/no_picture.gif)
UniProt Accession Number of Target Protein: P00533
Alternative Name(s) of Target: EGFR, ErbB-1, HER1; epidermal growth factor receptorImmunogen: The epidermal growth factor receptoris the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands.
Specificity: Recognises human EGFR.
Antibody first published in:Prewett M et al.The biologic effects of C225, a chimeric monoclonal antibody to the EGFR, on human prostate carcinoma.J Immunother Emphasis Tumor ImmunolPMID:9041461Note on publication:Describes effect of antibody on human prostate cancer.
Immunohistochemical staining of rat stomach tissue using anti-EGFR antibody (Ab00279) C225 (Cetuximab) Anti-EGFR staining of formaldehyde fixed paraffin embedded rat stomach tissue, at 40x magnification. The human IgG1-chimeric version of C225 (Ab00279-10.0) was used to stain samples at a concentration of 5 µg/ml.
Binding curve of anti-EGFR antibody to EGFR-Fc fusion protein ELISAPlate coated with human EGFR-Fc (Pr00117-10.9) at a concentration of 2.0 mg/ml. A 2-fold serial dilution from 100 to 0.1 ng/ml was performed using HRP labelled cetuximab human IgG1 (Ab00279-10.0).
