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当前位置: 首页 > 产品中心 > clinical_research > absoluteantibody/Ab00716-13.0 Anti-Integrin alpha 4 [Natalizumab]/Ab00716-13.0/200 µg
商品详细absoluteantibody/Ab00716-13.0 Anti-Integrin alpha 4 [Natalizumab]/Ab00716-13.0/200 µg
absoluteantibody/Ab00716-13.0 Anti-Integrin alpha 4 [Natalizumab]/Ab00716-13.0/200 µg
absoluteantibody/Ab00716-13.0 Anti-Integrin alpha 4 [Natalizumab]/Ab00716-13.0/200 µg
商品编号: Ab00716-13.0
品牌: absoluteantibody
市场价: ¥6384.00
美元价: 3830.40
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description: Recombinant monoclonal antibody to Integrin alpha 4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody Natalizumab.
Species and Isotype: Human IgG4, kappa
Clone Number: Natalizumab
UniProt Accession Number of Target Protein:
Published Application(s): block; FC
Published Species Reactivity: Human
Immunogen: The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
Specificity: This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin
Application Notes: This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
Antibody First Published in:
Sheremata et al. A safety and pharmacokinetic study of intravenous natalizumab in patients with MS Neurology. 1999 Mar 23;52(5):1072-4. PMID:10102433 Note on publication: Describes the safety and pharmacokinetic characterization of this antibody in a clinical setting.

Product Form

Purification: Protein A affinity purified
Supplied in: PBS with 0.02% Proclin 300.
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.

Important note – This product is for research use only. It is not intended for use in therapeutic or diagnostic procedures for humans or animals.
品牌介绍
Absolute antibody本公司服务于抗体测序、制造和工程服务提供给所有抗体使用者和不断增长的抗体。Absolute Antibody Ltd was founded in Oxford, UK, in August 2012, with the vision that all antibody users should be able to use recombinant antibodies, which are absolutely defined by their amino acid sequence. This view gained support in 2015 with a Comment in Nature magazine by Bradbury and Pluckthun (+110 co-signatories) – “Reproducibility: Standardize antibodies used in research“. Rather than creating entirely new antibodies (or antibody-like molecules), we are building a catalog by taking existing antibodies (often from hybridomas) then manufacturing them in a superior way and improving their usefulness by engineering.品牌货号名称规格absoluteantibody21 E11Anti-Api m 21 kitabsoluteantibodyBAB2Anti-Bet v 1 1 kitabsoluteantibodyBAB3Anti-Bet v 11 kitabsoluteantibodyBAB4Anti-Bet v 11 kitabsoluteantibodyBAB5Anti-Bet v 1 1 kitabsoluteantibodyBV16Anti-Bet v 1 1 kitabsoluteantibodyM0418Anti-Bet v 11 kitabsoluteantibody4C3Anti-Bla g 2 1 kitabsoluteantibody7C11Anti-Bla g 21 kitabsoluteantibodyD1Anti-Bos d 5 1 kitabsoluteantibody6A8Anti-Der f 11 kitabsoluteantibody10B9Anti-Der p 11 kitabsoluteantibody5H8Anti-Der p 11 kitabsoluteantibody4C1Anti-Neurotoxin AahII1 kitabsoluteantibodyH10Anti-Der p 21 kit